Thermophysical modeling of biological tissue cryoablation

Thermophysical modeling of novel machinable ceramic materials

Mathematical modeling of collagen turnover in biological tissue.

We present a theoretical and computational model for collagen turnover in soft biological tissues. Driven by alterations in the mechanical environment, collagen fiber bundles may undergo important chronic changes, characterized primarily by alterations in collagen synthesis and degradation rates. In particular, hypertension triggers an increase in tropocollagen synthesis and a decrease in colla...

Visualization of epicardial cryoablation lesions using endogenous tissue fluorescence.

BACKGROUND Percutaneous cryoballoon ablation is a commonly used procedure to treat atrial fibrillation. One of the major limitations of the procedure is the inability to directly visualize tissue damage and functional gaps between the lesions. We seek to develop an approach that will enable real-time visualization of tissue necrosis during cryo- or radiofrequency ablation procedures. METHODS ...

Gold nano-smolder for biological tissue manipulation

Thanks to their unique optical and electromagnetic properties, noble-metal nanoparticles are proven very useful in many scientific fields, from nanotechnology to biology, including detection of cancer cells. Irradiated gold nanoparticles, as a nano-smolder could be widely used in biomedical contexts such as tumor therapy. Laser destruction of a cancerous tissue depends on thermal and physical p...

inductive effect of palatal connective tissue on alveolar mocosa after subepithelial connective tissue graft clinical & histologic study

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